Licensed hemp acreage increased from 11,572 in 2019 to 405,863 in 2020 production season in North Carolina. This rapidly increasing market growth needs short-term and long-term strategies for farmers and CBD producers to further expand sustainably. Our overall hypothesis is that adopting the circular hemp and CBD industry is a major step in achieving greater sustainability in the Appalachian production regions. The project aims to assess the environmental, social, and economic impacts of agricultural hemp production for CBD oil in the Appalachian Regions, which will help farmers implement more sustainable practices. Second, eliminate hemp waste from CBD processing plants by integrating in-situ small anaerobic digesters (A.D.) and produce biogas, which will circulate back to hemp and/or CBD producers. This will enable circular hemp and CBD production in the Appalachian region including but not limited to states that currently produce hemp for CBD oil and further expand awareness and increase its adoption across the US.